Nick Naylor is a tobacco lobbyist. His job consists mainly of defending the tobacco industry. He also tries to remain a role model for his 12-year-old son Joey.
Joey is Nick's 12-year-old son.
Polly Bailey is Nick's friend and a lobbyist of the alcohol industry.
BR is Nick's boss at the Academy of Tobacco Studies.
Bobby Jay Bliss is Nick's friend and represents the lobby of the firearm industry.
Jill Naylor is Nick's ex-wife and Joey's mother.
Heather Holloway is a reporter for the newspaper Washington Probe who seduces Nick and then publishes an article about him.
The Captain is the founder of the Academy of Tobacco Studies
Ortolan Finistirre is Senator and fights with new laws against the tobacco industry.
Lorne Lutch the origina Marlboro Man who did advertisement for the tobacco industry.
Jeff Megall is a Hollywood super-agent.